Pharmacokinetic properties of mezlocillin in newborn infants

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Pharmacokinetic properties of mezlocillin in newborn infants.

The pharmacokinetic properties of mezlocillin were evaluated in newborn infants. Mean peak and trough concentrations of drug in plasma, after 75 mg of mezlocillin per kg given intravenously, were 252 and 72 micrograms/ml, respectively, in infants who were less than 38 weeks gestation and less than or equal to 7 days old, compared with 139 and 9 micrograms/ml, respectively, in infants greater th...

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The subject of cardiac hypertrophy unassociated with congenital malformation of the heart or great vessels in newborn infants has received scant attention. Although many text-books on pediatrics have been consulted, only one reference to the condition was found and that was by Von Reuss."1 He described a single case briefly and stated that the etiology was unknown. Recent studies indicate, howe...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1984

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.25.5.556